Every week, fantasy football owners hope there are no injuries, but we also know that a big injury, especially at RB, leads to the best pickups. So, again, while we definitely don’t root for guys to get hurt, we’re also quick see opportunity when they do. Our top Week 5 fantasy waiver wire pickups and free agent adds are headlined by such players, as Bears handcuff Damien Williams is line to be a starter for at least a game or two depending on the severity of David Montgomery’s knee injury and Trey Lance might be taking over at QB in San Francisco if Jimmy Garoppolo’s calf injury keeps him out. (Update: Garoppolo is expected to miss multiple weeks.) Fortunately, there weren’t many more key players who left games early, but plenty more potential breakouts had nice games, including Sam Darnold, Dawson Knox, Dalton Schultz, Van Jefferson, and Darnell Mooney.

Our full free agent list features many more interesting depth pieces coming off notable games. Guys like Quintez Cephus, Kenny Gainwell, Daniel Jones, Tyler Conklin, Curtis Samuel, Michael Carter, Maxx Williams, Randall Cobb, and DeVante Parker all have potential fantasy value, especially with the bye weeks fast approaching. These aren’t necessarily “must-haves,” but they’re certainly guys worth targeting as free agents depending on your team needs. If all you’re looking for is someone for Week 5, we have plenty of streaming suggestions at QB, WR, TE, and D/ST, which can be found at the end of this list. 

WEEK 5 PPR RANKINGS:
Quarterback | Running back | Wide receiver | Tight end | D/ST | Kicker

If Montgomery is expected to miss multiple games, Williams will be a worth a top waiver claim. Lance is a little tougher to evaluate. Most teams have a capable QB, but Lance’s dual-threat upside gives him top-10 potential every week. Of course, we said the same about Justin Fields and that hasn’t exactly turned out well. Because of that, using a top claim on Lance might be unnecessary, but it’s tough to watch him go to another team and light it up like we’ve seen from other rookie QBs in the past few years. It really comes down to your situation. If you have Kyler Murray or Patrick Mahomes, ignore Lance. If you drafted Ryan Tannehill to be your starter and don’t feel confident in your backup, maybe it’s worth the gamble.

WEEK 5 STANDARD RANKINGS:
Quarterback | Running back | Wide receiver | Tight end | D/ST | Kicker

No one else looks to be worth a top-five claim right now (we have two TEs among the top pickups, after all), but obviously that could change as more information comes out early in the week. We’ll stay on top of it so you know who’s worth adding. 

Top fantasy football waiver wire pickups for Week 5

Unless otherwise noted, only players owned in fewer than 50 percent of Yahoo leagues considered.

• #1

  Damien Williams, RB, Bears

  David Montgomery suffered what looked to be a potentially serious knee injury against the Lions, opening the door for Williams to take over as Chicago’s lead back. Williams looked good spelling Montgomery on Sunday, rushing eight times for 55 yards and a score and catching another two passes for another 15 yards. Yes, it was against Detroit late in a big win, but Williams has put up decent numbers for the Chiefs in the past, so he can work as an every-down back. He’ll be a top waiver pickup barring positive reports about Montgomery’s health. It’s worth noting that Tarik Cohen (knee) is eligible to come off the PUP list in Week 7 and could steal the bulk of the passing-down work when he’s back. — Matt Lutovsky

• Lance took over for Jimmy Garoppolo (calf) at the start of the second half. He had an up-and-down performance despite some eye-catching stats(157 passing yards, 41 rushing yards, two TDs passes, two-point conversion),but we caught glimpses of his tantalizing dual-threat potential even if most of his production came on a blown coverage and in garbage time. With Garoppolo expected to miss multiple games, Lance will be worth a waiver claim. Fantasy owners might be leery after hearing similar things about Justin Fields (and we’ve all seen how that’s turned out), but Lance is in a much more stable offense with a better play-caller. We’ll stop short of saying he’s “better” than Fields, especially given his college inexperience, but Lance certainly has a lot of upside and could have a major fantasy impact if he gets going. — ML

• #3

  Sam Darnold, QB, Panthers

  Darnold had some “Bad Sam” moments against the Cowboys, but fantasy owners can live with a few INTs if he’s going to keep passing for 300-plus yards and posting four overall scores. To sweeten the deal, Darnold even had 35 rushing yards. He’s now had 300 passing yards in three straight games (and at least 279 yards in all four games), and he’s rushed for five TDs on the season. He’ll be forced to do more with Christian McCaffrey (hamstring) out, and with the Eagles, Vikings, Giants, and Falcons on deck, he should continue to post pleasing fantasy stats. — ML

• #4

  Michael Carter, RB, Jets

  Carter had another week of being the lead back in the Jets’ offense. He totaled 14 touches for 34 total yards and a touchdown. While those aren’t eye-popping numbers, he’s worth the roster spot given his increased usage. He’ll play a bad Falcons’ defense in Week 5. — Jackson Sparks

• #5

  Dawson Knox, TE, Bills

  The Bills have a lot of mouths to feed on offense, so it always seemed risky to trust “TD-or-bust” Knox. This year, he’s been much more reliable, scoring in three straight games, including twice in Week 4. For the day, he caught five-of-eight targets for 37 yards. He’s caught four passes in three-of-four games this year, which doesn’t sound like a ton, but at TE, that’s valuable, especially in PPR leagues (and especially when it comes with a touchdown). Knox will have some duds, but that can be saidof almost all tight ends. The Bills can move the ball against anyone, and that will be especially true next week in Kansas City and the week after in Tennessee. — ML

• #6

  Dalton Schultz, TE, Cowboys

  Even though Blake Jarwin scored in Week 4, Schultz led the entire team in targets (8), catches (6), and scored his third TD in the past two games. With at least six targets in three-of-four games, he’s clearly Dallas’ lead TE, and that status puts him in play at such a weak position (especially in PPR formats). The Cowboys have one of the best offenses in the NFL, and they’ll continue moving the ball next week against the Giants. — ML

• #7

  Randall Cobb, WR, Packers

  Marquez Valdez-Scantling (knee) is on IR, so naturally, Cobb takes more of a role in the offense. Teams will often double-cover Davante Adams as Pittsburg did in Week 4 when Cobb caught five-of-six targets for 69 yards and two touchdowns. Let’s see if he carries the momentum into Week 5 against the Bengals. — JS

• #8

  Jamison Crowder, WR, Jets

  It wasn’t that long ago when Crowder was a solid PPR flex play, and he was just that in Week 4 against Tennessee. He drew nine targets for seven catches for 61 yards and a TD. He was productive with Sam Darnold, so he can do the same with Zach Wilson — especially in a matchup with the Falcons in London this week. — JS

• #9

  Darnell Mooney, WR, Bears

  Mooney finally had a breakout performance this year, catching five passes on seven targets for 115 yards. He looks more like Justin Fields’ favorite target than Allen Robinson right now. Mooney should be viewed as a decent PPR play moving forward, though not all matchups will be this favorable. He’ll take on the Raiders in Week 5. — JS

• #10

  Kenny Gainwell, RB, Eagles

  Gainwell was targeted seven times and rushed three times in Week 4. Overall, he totaled 89 yards of offense and only had one fewer touch than Miles Sanders (nine to 10). He’s been far more efficient than Sanders and found the end zone against Kansas City. In PPR leagues, he’s a solid depth piece. He plays Carolina in Week 5, and it remains to be seen how good their defense actually is after being torched by Dallas — JS

• #11

  Daniel Jones, QB, Giants

  Sam Darnold had more struggles against Dallas than we’ve seen so far this year, but he still threw a touchdown and rushed for two. Jones has the rushing skillset to produce a similar line, and Saquon Barkley, Kenny Golladay, and Kadarius Toney actually showed up in Week 4. Jones is a mid-tier QB2 vs. Dallas in Week 5 after a big Week 4 against a New Orleans defense that had been solid this year (402 passing yards, 27 rushing yards, two TDs). — JS

• #12

  Curtis Samuel, WR, Washington

  Samuel returned from the IR on Sunday, and even though he had a relatively quiet day (four catches, 19 yards), he’s going to be a big part of Washington’s offense going forward. Grab him now and enjoy the production against New Orleans and Kansas City the next two weeks. — ML

• #13

  Emmanuel Sanders, WR, Bills

  We’re confused why Sanders is still available in more than 50 percent of Yahoo leagues, but surely this will be the last week that statement remains true. In a game where the Bills dominated, Sanders caught five-of-six targets for 74 yards. Next week, he’ll play the Chiefs, and we might see Josh Allen and Patrick Mahomes break the record for the most combined passing attempts. Sanders is an instant high-end flex consideration in Week 5. –JS

• #14

  Van Jefferson, WR, Rams

  Jefferson caught all six of his targets for 90 yards and a touchdown in Week 4. He is the more reliable option between him and DeSean Jackson, but neither are must-starts. Jefferson might come and go in the Rams loaded offense, but he’s worth roster consideration heading into a matchup with a bad Seattle secondary in Week 5. — JS

• #15

  DeVante Parker, WR, Dolphins

  Parker was written off prior to his season, but he’s arguably been the best Dolphins’ WR. In Week 4, he caught four-of-nine targets for 77 yards and a touchdown. Also, WIll Fuller (hand) is banged up, which obviously opens more opportunities for Parker. Tua Tagovailoa will eventually return from a rib injury, and you’d have to think he’ll have more success through the air than Jacoby Brissett. Parker will play the Buccaneers in Week 5, who have given pass-catchers whatever they want. — JS

• #16

  A.J. Green, WR, Cardinals

  Green once again looked like his former self, catching five-of-six targets for 67 yards and a touchdown in Week 4. This offense is producing a ridiculous amount of fantasy points, and this is your chance to get a piece of it. They’ll play the 49ers in Week 5, and they’ve been torched several times this season. — JS

• #17

  Tyler Conklin, TE, Vikings

  The entire Minnesota offense was at a standstill vs. Cleveland, but Conklin did draw six targets for four catches. He’s not a sit ’em and forget ’em option at tight end, but he’s a high-upside streamer against the Lions in Week 5. — JS

• #18

  Josh Reynolds, WR, Titans

  Reynold led all Tennessee WRs in targets (9) in the absence of A.J. Brown (hamstring) and Julio Jones (leg) in Week 4. That said, he’s valuable while those two are out — especially in a matchup with Jacksonville next week. — JS

• #19

  Quintez Cephus, WR, Lions

  Despite how awful the Lions’ offense has looked, it hasn’t stopped it from having fantasy-relevant options. Cephus caught four-of-five targets for 83 yards and continues to look like the big-play threat in Detroit. He’ll play Minnesota in Week 5, and while they’ve looked improved on defense, we still view this as a favorable matchup. — JS

• #20

  Kalif Raymond, WR, Lions

  In Week 4, Raymond caught three-of-six targets for 35 yards and two touchdowns. It’s tough to love a player based on just touchdowns, but this is his second straight week with solid production. Lions’ OC Anthony Lynn continues to draw up plays for him, so he should continue to get opportunities. In deep leagues, he’s a flex consideration heading into a matchup with Minnesota. –JS

• #21

  Kadarius Toney, WR, Giants

  The rookie first-round pick was finally a factor in Week 4. He caught six-of-nine targets for 78 yards and had a rushing attempt. Simply put, someone has to catch footballs on this offense, and with Darius Slayton and Sterling Shepard dealing with hamstring injuries, Toney should continue to benefit in a Week 5 matchup with Dallas. — JS

• #22

  Sammy Watkins, WR, Ravens

  Watkins caught four-of-seven targets for 49 yards in Week 4 and continues to exceed his preseason expectations. Rashod Bateman (core) might play next week, so Watkins could take more of a backseat, but for now, Watkins is worth a roster spot heading into a matchup with Indianapolis. — JS

• #23

  Malcolm Brown, RB, Dolphins

  Brown did nothing noteworthy against the Colts, but he did get the most touches of any Dolphins RB, as Myles Gaskin was seemingly phased out. He also saw the goal-line carries in Week 3. You don’t want to start him yet, but it’s always worth monitoring a lead RB in any offense. He’ll play Tampa Bay in Week 5, so he’s not an option there, but he’s worth stashing with the bye weeks soon approaching. — JS

• #24

  Samaje Perine, RB, Bengals

  Joe Mixon has dominated touches in this backfield, but he appeared to tweak his ankle late in the game against Jacksonville. Mixon has been due for injuries in each year of his career, so Perine now becomes one of the more attractive handcuff RBs. He could be a top pickup this week if there are negative reports about Mixon. — JS

• #25

  Marlon Mack, RB, Colts

  As the season progresses, more RBs continue to get banged up. We saw David Montgomery and Tony Jones Jr. go down this week, so Mack could be traded at any moment to an RB-needy team. If you have a roster spot, stash him now. — JS

• #26

  Rashod Bateman, WR, Ravens

  Like Tre’Quan Smith and T.Y. Hilton, there’s a chance Bateman makes his season debut in Week 5. — JS

• #27

  T.Y. Hilton, WR, Colts

• #28

  Tre’Quan Smith, WR, Saints

• #29

  Josh Gordon, WR, Chiefs

  Gordon is worth rostering if you have the room. If nothing else, he’s a free flyer at possible flex production. – -JS

• #30

  Jameis Winston, QB, Saints

  Winston hasn’t been what we hoped he’d be, but he’s still worth watching. This offense has been up and down through four weeks, but we have to think they’ll eventually settle in, especially with Tre’Quan Smith (hamstring) and Michael Thomas (ankle) set to return at some point this season. That said, he has the chance to be a solid option later in the season. For streaming purposes, Winston plays Washington in Week 5, and they’ve been a shockingly bad pass defense this season. — JS

• #31

  Hunter Henry, TE, Patriots

  Henry scored last week and tied Jonnu Smith in targets (5) a week after seeing six targets. He seems to be emerging slightly over Smith despite Smith also scoring, and he’s in play against a bad Texans defense. —ML

• #32

  Jonnu Smith, TE, Patriots

  Smith has seen at least five targets in four straight games, and he finally found the end zone last week. He still had just 14 yards, but he’s in play this week against the Texans’ porous defense. — ML

• #33

  Mo Alie-Cox, TE, Colts

  Alie-Cox is back to scoring TDs. Our preseason deep sleeper at TE caught three passes for 42 yards and two touchdowns in Week 4. As usual, he’s much more attractive in standard leagues, but perhaps he can build on this momentum heading into Week 5 against Baltimore — JS

• #34

  C.J. Uzomah, TE, Bengals

  Uzomah had the best game of his career against Jacksonville, catching five-of-six targets for 95 yards and two touchdowns. This performance might be an anomaly, but it’s worth monitoring him moving forward at such an unproductive position in fantasy football (especially if Tee Higgins misses more times). — JS

• #35

  Maxx Williams, TE, Cardinals

  Williams caught all five of his targets against the Rams, and he’s been one of the top breakout tight ends this season. This offense is loaded and puts up a ton of points every week. Williams is a great flyer. He’ll play San Francisco in Week 5 in what could be another NFC West shootout. – -JS

• #36

  Cameron Brate, TE, Buccaneers

  Rob Gronkowski (ribs) was inactive for Week 4 and it looks like he might miss a few weeks down the road. It seems as if Brate is the next man in line to serve as the primary tight end, but O.J. Howard will also get a chance to compete for that role. For now, Brate is the more attractive option, as he’s been a real weapon in the red zone throughout his career and had five more targets than Howard in Week 4. He’s never been the sole starting tight end in an offense, yet he’s caught 29 touchdowns in his seven-year career. That said, he looks like an attractive temporary Gronk replacement in standard leagues. — JS

• #37

  Ricky Seals-Jones, TE, Washington

  With Logan Thomas (hamstring) leaving early in Week 4, Seals-Jones took over at TE and caught two-of-four targets for 19 yards. Given RSJ’s athleticism and how often Washington throws to TEs, RSJ could have some value if Thomas misses games. He gets New Orleans and Kansas City the next two weeks. — ML

• #38

  Carolina Panthers DST

  This defense might get exposed by Dallas in Week 4, but the Eagles’ offense has looked bad against decent defenses this year. Here’s another spot for Carolina to look dominant on that side of the ball. — JS

• #39

  Las Vegas Raiders DST

  Did anyone see how bad Justin Fields and the Bears’ offensive line looked against Cleveland? It made mistakes against the Lions putrid defense, too.The Raiders have an underrated pass rush, so they have to be considered as a streamer at the D/ST spot in Week 5. — JS

• #40

  Minnesota Vikings DST

  Mike Zimmer should eventually get this defense right, and what a better time to start than a matchup with Jared Goff, whose best WR is Kalif Raymond or Quintez Cephus. This Lions’ offense is limited and Goff is always prone to turnovers. — JS

• #41

  Philadelphia Eagles DST

  The Panthers offense showed few ill effects of Christian McCaffrey being out in Week 4, but Sam Darnold made some key mistakes while playing from behind. The Eagles’ defense is nothing special, but they have some boom-or-bust streamer appeal here. — ML

• The Falcons might have the worst defense in football, but the Jets have the worst offense. Falcons defense coordinator Dean Pees has orchestrated some of the toughest defenses in recent memory with New England and Baltimore, and we have to think he’s not going to let Zach Wilson have a field day here. — JS